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10 p, 762.5 KB The Influence of DAT1, COMT, and BDNF Genetic Polymorphisms on Total and Subregional Hippocampal Volumes in Early Onset Heavy Cannabis Users / Batalla, Albert (Radboud University) ; Lorenzetti, Valentina (Monash University) ; Chye, Yann (Monash University) ; Yücel, Murat (Monash University) ; Soriano-Mas, Carles (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de Ciències de la Salut) ; Bhattacharyya, Sagnik (King's College London. Institute of Psychiatry, Psychology & Neuroscience) ; Torrens, Marta (Institut Hospital del Mar d'Investigacions Mèdiques) ; Crippa, José A. S. (Instituto Nacional de Ciência e Tecnologia Translacional em Medicina Translational Medicine (INCT-TM)) ; Martín-Santos, Rocío (Institut Hospital del Mar d'Investigacions Mèdiques)
Introduction: Hippocampal neuroanatomy is affected by genetic variations in dopaminergic candidate genes and environmental insults, such as early onset of chronic cannabis exposure. Here, we examine how hippocampal total and subregional volumes are affected by cannabis use and functional polymorphisms of dopamine-relevant genes, including the catechol-O-methyltransferase (COMT), dopamine transporter (DAT1), and the brain-derived neurotrophic factor (BDNF) genes. [...]
2018 - 10.1089/can.2017.0021
Cannabis and Cannabinoid Research, Vol. 3 (february 2018) , p. 1-10  
Detailed record - Creative Commons

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